Beware of repeated dengue afflictions

Docs Warn That Fatality Risk Increases Due To Reaction Between Antibodies Present In The Body From Primary & Secondary Infections
Even as dengue ravages Kerala, health experts are confused by the uncommon traits and complications that were recently observed in patients.

The pattern of dengue deaths also indicates that mortality rate was high among patients who were repeatedly diagnosed with the disease.

If a person gets dengue for the first time (type-I), proper rest and medication will help in combating fever and antibodies will be generated in the body that will give life-long immunity against the type-I variety. But, when the same person is exposed to mosquito bites and gets dengue (type-II or type-III), a new set of antibodies will be generated in the body. Antibodies generated in the primary infection and secondary infection react, resulting in grave complications that may even lead to the death of the patient.

Through virus uptake and replication, type-I antibodies will intensify and complicate the typeII virus by a process called antibody dependent immune enhancement. “When a person is tested positive for dengue, prescribed antibiotics will only treat the symptoms of fever and not the virus.Like any other viral fever, dengue virus will subside and antibodies will be generated in a week. When a person is affected by dengue twice or thrice, the reaction of subsequent antibodies will lead to internal bleeding and cause dengue haemorrhagic fever or dengue shock syndrome that may lead to death,” said associate professor of community medicine at Thiruvananthapuram medical college Dr Althaf A.

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